1500 – 1852 – Bunyoro Kitara Kingdom: Bito dynasties of Buganda, Bunyoro and Ankole founded by Nilotic-speaking immigrants from the current southeastern Sudan. Expansion of Buganda at the expense of Bunyoro and take control of the territory bordering Lake Victoria from the Victoria Nile to the Kagera river.
1862 – The first European, British explorer John Hanning Speke visits Buganda.
1875 – Christian missionaries are allowed to enter the realm of Buganda King Mutesa 1.
1890 – A treaty signed between Britain and Germany gives Britain rights to what was to become Uganda.
1894 – Uganda becomes a British protectorate.
1900 – Britain signs an agreement with Buganda giving it autonomy and turning it into a constitutional monarchy controlled mainly by Protestant chiefs.
1958 – Uganda granted internal self-government.
1962 – Uganda becomes independent with Milton Obote as prime minister and with Buganda enjoying considerable autonomy.
1963 – Uganda becomes a republic with Buganda’s King Mutesa – Edward Luwangula Walugembe Muteesa II – as president.
1966 – Milton Obote ends Buganda’s autonomy and promotes himself to the presidency.
1967 – New constitution vests considerable power in the president.
1971 – Milton Obote toppled in coup led by Army chief Idi Amin.
1972 – Around 60,000 Asians Ugandan citizens expelled by Amin from Uganda.
1976 – Idi Amin declares himself president for life and lays claims to parts of Kenyan territory.
1978 – 1979 – The Uganda – Tanzania war known as the Kagera War in Tanzania and The 1979 Liberation War oust president Idi Amin from power.
1979 – Tanzanian forces invade Uganda, unifying the various anti-Amin forces under the Uganda National Liberation Front. Amin flees out of the country; Yusuf Lule installed as president, but quickly replaced by Godfrey Binaisa.
1980 – After elections Milton Obote returns as the president of Uganda.
1985 – Milton Obote is deposed in a military coup and replaced by Tito Okello. The new military leaders Tito Okello, Bazilio Olara Okello and Gad Wilson Toko hold onto the presidency for under a year before they are also ousted from power by the National Resistance Army (NRA) on January 26, 1986.
1986 – Yoweri Museveni becomes president after National Resistance Army rebels gain control of Kampala.
1993 – Yoweri Museveni restores the traditional kings, including the king of Buganda, but stripped of their political power.
1995 – The new constitution legalises political parties but maintains the ban on political activity.
1996 – Museveni returned to office in Uganda’s first direct presidential election.
1998 – Ugandan troops intervene in the Democratic Republic of Congo on the side of rebels seeking to overthrow Kabila.
2000 – Ugandans vote in favour of continuing Museveni’s “no-party” system rejecting multi-party politics.
2001 – Museveni wins a new term in office, beating his rival Kizza Besigye by 69% to 28%.
2005 July – Parliament approves a constitutional amendment which scraps presidential term limits. Voters in a referendum overwhelmingly back a return to multi-party politics.
2005 November – Kizza Besigye, opposition leader is imprisoned shortly after returning from exile having undergone a trial in a military court on various charges including treason and illegal possession of firearms. Supporters claim the trial is politically motivated, and take to the streets. Besigye is released on bail in January 2006, ahead of presidential elections.
2006 February – President Museveni wins multi-party elections, taking 59% of the vote against the 37% of his rival, Kizza Besigye. EU observers highlight intimidation of Mr Besigye and official media bias.
2010 October – Constitutional Court quashes treason charges against opposition leader Kizza Besigye.
2011 February – Museveni wins his fourth presidential election. Challenger Kizza Besigye alleges vote-rigging and dismisses the election result as a sham.
2011 April – Kizza Besigye arrested several times over ”walk-to-work” protests against rising fuel prices.
2016 February – President Museveni wins re-election against veteran candidate Kizza Besigye, amid opposition, Commonwealth, US and European Union concern about fairness and transparency of the electoral process.
2017 January – President Museveni appoints his son, General Muhoozi Kainerugaba, as a presidential advisor
2017 April – Former musical artist Robert Kyagulanyi Ssentamu popularly known by stage name Bobi Wine wins a by-election to become the legislator for Kyadondo County East against formidable opposition and draws attention in Uganda and abroad.
2017 December – Parliament votes to remove the age-limit for presidential candidates, clearing the way for President Museveni to run for another term.
2018 – The arrest and torture of Robert Kyagulanyi Ssentamu known as “Ghetto president” ignites popular protests with demands for his release.
2019 – Ugandan Musician and opposition leader Bobi Wine announced he’ll run for president in 2021, in an effort to thwart President Yoweri Museveni, who has been in power in Uganda since 1986
2020 – Political fever spikes as Uganda elections near with Bobi Wine running in 2021. Kizza Besigye challenged Museveni four times since 2001 and is no longer going to contest any election organized under the ruling NRM. Gregory Mugisha Muntuyera, the former Forum for Democratic Change (FDC) president, and Bobi Wine have joined forces in a new alliance called the United Forces of Change.